Publications
Babulab Publications
Original Research Articles
Pratima Pandey, Ashwani Bhardwaj and Kavita Babu© (2017); Regulation of WNT Signaling at the Neuromuscular Junction by the Immunoglobulin Super-Family Protein RIG-3 in Caenorhabditis elegans . Genetics 2017 Jul 01; 206(3): 1521 -34. http://www.genetics.org/content/206/3/1521.long
Shruti Thapliyal, Amruta Vasudevan*, Yongming Dong*, Jihong Bai, Sandhya P. Koushika and Kavita Babu© (2018); The C-terminal of CASY-1/Calsyntenin regulates GABAergic synaptic transmission at the Caenorhabditis elegans neuromuscular junction. PLoS Genetics 2018 Mar; 14(3): e1007236. http://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1007263
This work was highlighted by the Wellcome Trust- DBT India Alliance website.
Shruti Thapliyal, Shruthi RavindranathU and Kavita Babu© (2018); Regulation of glutamate signaling in the sensorimotor circuit by CASY-1A/Calsyntenin in Caenorhabditis elegans. Genetics 2018 Apr 01; 208(4): 1553-64. http://www.genetics.org/content/208/4/1553.long
This work was highlighted by the Wellcome Trust- DBT India Alliance website.
Ashwani Bhardwaj*, Saurabh Thapliyal*U, Yogesh Dahiya and Kavita Babu© (2018); FLP-18 functions through the G-protein coupled receptors NPR-1 and NPR-4 to modulate reversal length in Caenorhabditis elegans. The Journal of Neuroscience 2018 May 16; 38(20): 4641-54. http://www.jneurosci.org/content/38/20/4641.long
Mentioned on This week in the journal by Teresa Esch. The Journal of Neuroscience 2018 May 16; 38(20) i.
Press Release from The Journal of Neuroscience for this work:
https://www.eurekalert.org/pub_releases/2018-04/sfn-buh042418.php
https://phys.org/news/2018-04-neuropeptide-roundworms-movement.html
This work was highlighted by the Wellcome Trust- DBT India Alliance website.
Pallavi Sharma*, Lei Li*, Haowen Liu, Vina Tikiyani, Zhitao Hu© and Kavita Babu© (2018); The Claudin-like protein, HPO-30, is required to maintain LAChRs at the Caenorhabditis elegans neuromuscular junction. The Journal of Neuroscience 2018 Aug 08; 38(32): 7072-87. http://www.jneurosci.org/content/38/32/7072.long
This work was highlighted by the Wellcome Trust- DBT India Alliance website.
Vina Tikiyani, Lei Li, Pallavi Sharma, Haowen Liu, Zhitao Hu and Kavita Babu© (2018); Wnt secretion is regulated by the tetraspan protein HIC-1 through its interaction with Neurabin/NAB-1. Cell Reports 2018 Nov 13; 25(7): 1856-71. https://www.cell.com/cell-reports/fulltext/S2211-1247(18)31642-5
This work was highlighted by the Wellcome Trust- DBT India Alliance website.
Raunaq Deo*, Manish S. Kushwah*, Sukrut C. Kamerkar, Nagesh Y. Kadam, Srishti Dar, Kavita Babu, Anand Srivastava and Thomas J. Pucadyil© (2018); ATP-dependent membrane remodeling links EHD1 functions to endocytic recycling. Nature Communications 2018 Dec 5; 9(1): 5187. https://www.nature.com/articles/s41467-018-07586-z
Yogesh Dahiya©, Saloni RoseU, Shruti Thapliyal, Shivam BhardwajU, Maruthi PrasadU and Kavita Babu© (2019); Differential regulation of innate and learned behavior by CREB1/CRH-1 in Caenorhabditis elegans. The Journal of Neuroscience 2019 Oct 2; 39(40): 7934-46. https://www.jneurosci.org/content/39/40/7934.long
bioRxiv Preprint: https://www.biorxiv.org/content/early/2019/01/04/508986.
Ashwani Bhardwaj*, Pratima Pandey* and Kavita Babu© (2020); Control of locomotory behavior of Caenorhabditis elegans by the immunoglobulin superfamily protein RIG-3. Genetics 2020 Jan 01; 214(1): 135-45. https://www.genetics.org/content/214/1/135
Nagesh Kadam©, Sukanta BeheraU, Sandeep Kumar, Anindya Ghosh-Roy and Kavita Babu© (2021); The G-protein coupled receptor SRX-97 is required for concentration dependent sensing of benzaldehyde in Caenorhabditis elegans. eNeuro 2021 Jan 04; 8(01):ENEURO.0011-20.2020. https://www.eneuro.org/content/8/1/ENEURO.0011-20.2020.long
bioRxiv Preprint: https://www.biorxiv.org/content/10.1101/2020.01.04.894824v1.
This work was highlighted by the Wellcome Trust- DBT India Alliance website at https://www.indiaalliance.org/news/how-animals-smell
Pratima Pandey*©, Anuradha Singh*, Harjot Kaur, Anindya Ghosh-Roy and Kavita Babu© (2021); Increased dopaminergic neurotransmission results in ethanol dependent sedative behaviors in Caenorhabditis elegans. PLoS Genetics 2021 Feb 01; 17(2):e1009346. https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1009346
bioRxiv Preprint: https://www.biorxiv.org/content/10.1101/779405v1.
Reviews, Protocols and other publications
Shruti Thapliyal and Kavita Babu© (2018); Pentylenetetrazole (PTZ)-induced Convulsion Assay to Determine GABAergic Defects in Caenorhabditis elegans (invited protocol). Bio-protocol 2018 Sep 05; 8(17). https://bio-protocol.org/e2989
Shruti Thapliyal© and Kavita Babu© (2019); C. elegans Locomotion: Finding Balance in Imbalance (invited review for the special edition of a Springer book). Advances in Experimental Medicine and Biology 2019 Jan 13; 1112: 185-96. https://link.springer.com/chapter/10.1007%2F978-981-13-3065-0_14
Kavita Babu© and Sandhya P Koushika© (2019); Sydney Brenner (1927-2019). Current Science 2019 Jun 25; 16(12): 2106-09. https://www.currentscience.ac.in/Volumes/116/12/2106.pdf
Vina Tikiyani© and Kavita Babu©(2019); Claudins in the brain: Unconventional functions in neurons. Traffic 2019 Nov 01; 20(11): 807-14. https://onlinelibrary.wiley.com/doi/10.1111/tra.12685
Kavita Babu© (2020); Sticking and signalling at the synapse: two sides of the same coin? Resonance 2020 Mar; 25(3): 419-29. https://www.ias.ac.in/article/fulltext/reso/025/03/0419-0429 This was an invited pedagogical piece for a special issue of Resonance on Women in Science.
Umer S. Bhat© and Kavita Babu© (2020); Neuropeptides: the slower neurotransmitters. Resonance 2020 Dec; 25(12): 1741-52. https://www.ias.ac.in/article/fulltext/reso/025/12/1741-1752. This was a pedagogical piece.
Key
* — Equal contribution, © — Corresponding author/s, and u — Undergraduate student
Prior Publications
Dr. Kavita Babu
Babu, K., Hu, Z., Chien, S-C., Garriga, G. and Kaplan, J.M. (2011) The Immunoglobulin super family protein RIG-3 prevents synaptic potentiation and regulates Wnt signaling. Neuron Jul 14; 71(1):103-16.†
Hu, Z.*, Pym, E.C.G.*, Babu, K.*, Vahlishan Murray, A.B.* and Kaplan, J.M. (2011) A neuropeptide-mediated stretch response links muscle contraction to changes in pre-synaptic release of neurotransmitter. Neuron Jul 14; 71(1):92-102.†
Babu, K.©, Bahri, S., Alphey, L. and Chia, W. (2005) Bifocal and PP1 interaction regulates targeting of the R-cell growth cone in Drosophila. Dev Biol Dec 15; 288(2): 372-86.†
Babu, K., Cai, Y., Bahri, S., Yang, X. and Chia, W. (2004) Roles of Bifocal, Homer and F-actin in anchoring Oskar to the posterior cortex of Drosophila oocytes. Genes Dev. Jan 15; 18(2): 138-43.†
Helps, N.R.*, Cohen, P.T., Bahri, S.M., Chia, W. and Babu, K.* (2001) Interaction with protein phosphatase 1 Is essential for bifocal function during the morphogenesis of the Drosophila compound eye. Mol Cell Biol. Mar: 21(6): 2154-64.†
Dr. Pratima Sharma Pandey
Pandey, P. and Dhillon, H. S. (2012) The Caenorhabditis elegans D2-like dopamine receptor DOP-2 physically interacts with GPA-14, a G-alpha-i subunit. J Molecular Signaling Dec 5; 8(1): 13.†
Pandey, P., Pierpont, T. and Dhillon, H. S. (2010) An alternatively spliced version of dop-2, a D2-like receptor gene. The Worm Breeders Gazette 18 (2):25.†
Howard, R. A., Sharma, P., Hajjar, C., Caldwell, K. A., Caldwell, G. A., du Breuil, R., Moore, R. and Boyd, L. (2007) Ubiquitin conjugating enzymes participate in polyglutamine protein aggregation. BMC Cell Biol. July 30; 8(32).†
Sharma, P. and Mondal A.K. (2006) Evidence that the MAPK-docking site in MAPKK Dpbs2p is essential for its function. Biochem Biophys Res Commun. July 28; 346(2):562-6.†
Sharma, P. and Mondal, A.K. (2005). Evidence that C-terminal non-kinase domain of Pbs2p has a role in high osmolarity-induced nuclear localization of Hog1p. Biochem Biophys Res Commun. Mar 25; 328(4):906-13.†
Sharma, P., Meena, N., Aggarwal, M. and Mondal, A.K. (2005). Debaryomyces hansenii, a highly osmo-tolerant and halo-tolerant yeast, maintains activated Dhog1p in the cytoplasm during its growth under severe osmotic stress. Current Genetics Sep; 48(3):162-70. †
Bansal, P. K.*, Sharma, P.*, and Mondal, A.K. (2001). A PBS2 homologue from Debaryomyces hansenii shows differential effect on calcoflour and polymyxin B sensitivity in Saccharomyces cerevisiae. Yeast. Oct; 18:1207-1216.†
Bansal, P. K., Sharma, P., and Mondal, A.K. (2001). A minisatellite sequence in the upstream region of the DURA3 gene from the halotolerant yeast Debaryomyces hansenii. Yeast. Sep 30; 18(13):1301-1307.†
Dr. Yogesh Dahiya
Pandey, R. K., Sodhi, A., Biswas, S.K., Dahiya, Y., Dhillon, M.K. (2012) Mycobacterium indicus pranii mediates macrophage activation through TLR2 and NOD2 in a MyD88 dependent manner. Vaccine Aug; 30(39):5748-5754.†
Pandey, R. K., Dahiya, Y., Sodhi, A. (2012) Mycobacterium indicus pranii downregulates MMP-9 and iNOS through COX-2 dependent and TNF-α independent pathway in mouse peritoneal macrophages in vitro. Microbes Infect. Apr; 14(4):348-356.†
Dahiya, Y., Pandey, R. K., Sodhi, A. (2011) Nod2 downregulates TLR2/1 mediated IL1β gene expression in mouse peritoneal macrophages. PLoS One. 6(11):e27828.†
Pandey, R. K., Bhatt, K. H., Dahiya, Y., Sodhi, A. (2011) Mycobacterium indicus pranii supernatant induces apoptotic cell death in mouse peritoneal macrophages in vitro. PLoS One. Feb; 6(2):e17093.†
Dahiya, Y., Pandey, R. K., Bhatt, K. H., Sodhi, A. (2010). Role of prostaglandin E2 in peptidoglycan mediated iNOS expression in mouse peritoneal macrophages in vitro. FEBS Letters Oct 8; 584(19):4227-4232.†
Bhatt, K. H., Pandey, R. K., Dahiya, Y., Sodhi, A. (2010). Protein kinase C delta and protein tyrosine kinase regulate peptidoglycan-induced nuclear factor-kappaB activation and inducible nitric oxide synthase expression in mouse peritoneal macrophages in vitro. Molecular Immunology Jan; 47(4):861-870.†
Dr. Vandita Bhat
Qiu, C.*, Bhat, V. D.*, Rajeev, S., Zhang, C., Laslet, A. E., Wine, R. N., Campbell, Z. T., Tanaka Hall, T. M. (2019). A crystal structure of a collaborative RNA regulatory complex reveals mechanisms to refine target specificity. eLife Aug 9; 8:e48968.†
Bhat, V. D.*, McCann, K. L.*, Wang, Y., Fonseca, D. R., Shukla, T., Alexander, J. C., Qiu, C., Wickens, M., Lo, T. W., Tanaka Hall, T. M., Campbell, Z. T. (2019). Engineering a conserved RNA regulatory protein repurposes its biological function in vivo. eLife Jan 17; 8:e43788.†
Zhou, Q., Kunder, N., De la Paz, J. A., Lasley, A. E., Bhat, V. D., Morcos, F., Campbell, Z. T. (2018). Global pairwise RNA interaction landscapes reveal core features of protein recognition. Nature Communications Jun 28; 9(1):2511.†
Barragán-Iglesias, P., Lou, T. F., Bhat, V. D., Megat, S., Burton, M. D., Price, T. J., Campbell, Z. T. (2018). Inhibition of Poly(A)-binding protein with a synthetic RNA mimic reduces pain sensitization in mice. Nature Communications Jan 2; 9(1):10.†
Ashwani Bhardwaj
Guleria, S., Tiku, A. K., Singh, G., Vyas, D., Bhardwaj, A. (2011) Antioxidant Activity and Protective Effect Against Plasmid DNA Strand Scission of Leaf, Bark, and Heartwood Extracts from Acacia catechu. J Food Sci. Sep; 76(7):C959-964.†
Navneet Shahi
Balasubramanian, N., Sagarkar, S., Jadhav, M., Shahi, N., Sirmaur, R., Sakharkar, A. J. (2020) Role for histone deacetylation in traumatic brain injury-induced deficits in neuropeptide Y in arcuate nucleus: Possible implications in feeding behaviour. Neuroendocrinology.†
Key
† — Publication prior to joining the Babu lab